NPC's

Domino City

 * Yami Yugi
 * Seto Kaiba
 * Joey Wheeler
 * Mai Valentine
 * Bandit Keith
 * Maximillion Pegasus
 * Yami Bakura
 * Yami Marik
 * Yugi Muto

Duel Academy

 * Jaden Yuki
 * Chazz Princeton
 * Alexis Rhodes
 * Syrus Truesdale
 * Hell Kaiser
 * Vellian Crowler
 * Aster Phoenix
 * Jesse Anderson

Neo Domino City/Satellite

 * Yusei Fudo
 * Jack Atlas
 * Akiza Izinski
 * Leo
 * Luna
 * Crow Hogan
 * Carly Carmine
 * Kalin Kessler

YuGiOh Online Exclusive NPCs

 * BeeBee
 * bankara
 * Joker
 * KC Dragon
 * gouk
 * Miss Shadow
 * Miss Scout
 * Robert
 * ZuruZuru
 * frogMaster
 * kyoko
 * missbomb
 * Reia
 * Sakura
 * kanna
 * dancer
 * Zuno
 * A-lien
 * Kain
 * Brow
 * raMon
 * NiaNia
 * Rain
 * Mika
 * lalala
 * AoJ
 * Kyuros
 * Queen Ryo
 * Abigail
 * sabasaba
 * Elly
 * Gallum
 * Force